Integrative Immunology (i2)
description
The i2 theme tackles the global analysis and modeling of the complexity of the immune system. As part of the i3 laboratory, its contribution is to
- enlarge the frontiers of immunology in the context of complex systems with theoretical and experimental approaches, notably through our ImmunoComplexiT network,
- participate to medical research diagnosis and therapies, therefore contributing to the overall “bench to bedside” research strategy proposed at the level of the research unit,
- promote and develop systems immunology by the development of new statistical analysis strategies, as well as computer modeling and simulation schemes,
- contribute actively to the training of young researchers in the laboratory (MSc, PhD, postdoc) as well as at the university level with particular involvement for this critical societal & cultural stake.
Affiliations
Contact info
Address: i2 - Integrative Immunology, Inserm UMRS 959 - Sorbonne Université, Bâtiment CERVI, CHU Pitié-Salpêtrière, 83 boulevard de l'HôpitalCity: Paris
Postal code: 75013
Region: Ile-de-France
Telephone: +33 1 42 17 65 11
Fax: +33 1 42 17 65 17
Website: http://www.i3-immuno.fr
Top Publications
- Barennes P, Quiniou V, Shugay M, Egorov ES, Davydov AN, Chudakov DM, Uddin I, Ismail M, Oakes T, Chain B, Eugster A, Kashofer K, Rainer PP, Darko S, Ransier A, Douek DC, Klatzmann D, Mariotti-Ferrandiz E
Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases
Nature Biotechnology, 2020 - Ritvo PG, Saadawi A, Barennes P, Quiniou V, Chaara W, El Soufi K, Bonnet B, Six A, Shugay M, Mariotti-Ferrandiz E, Klatzmann D
High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells
Proc Natl Acad Sci USA. 2018, 115(38):9604-9609 - Chaara W, Gonzalez A, Florez L, Klatzmann D, Mariotti-Ferrandiz E, Six A
Representativeness and robustness of TCR repertoire diversity assessment by high-throughput sequencing
Frontiers in Immunology 2018, 9:1038 - Thomas-Vaslin V
Understanding and modeling the complexity of the immune system, In: First complex systems digital campus world E-conference 2015 Springer Proceedings in Complexity
Springer, Cham 2017, 261-270