WP3

UVEREG

​Treatment of the Bilateral Severe Uveitis by IVT of Regulator T-cells: Study of Tolerance of Dose​
Uveitis is a leading cause of blindness in the children and young adult's populations. One third of etiology are idiopathic. The ...
WP3

DFIL2

​Dose-effect Relationship of Low-dose IL-2 in Type 1 Diabetes​ 
IL-2 is an inducer of regulatory T cells (Treg), a population of lymphocytes that fail to control the autoimmune destruction of beta-cells in patients with Type 1 D...
WP3

DIABIL2

​European phase-II clinical trial evaluating efficacy of low dose rhIL-2 in patients with recently-diagnosed type 1 diabetes​
Clinical and preclinical studies, together with supportive mechanistic da...
WP3

TRANSREG

​TRANSREG is a multicentric, uncontrolled, open-label study, comparing biological and clinical responses to the administration of low dose of IL-2 across 11 selected pathologies (12 patients/pathology): rheumatoid arthritis, ankylosing spondyliti...
LabEx

Transimmunom

Phenomics in Autoimmune and Inflammatory Diseases​​
The family of inflammatory/autoimmune systemic diseases (IAD) form a continuum from pure inflammatory diseases to pure autoimmune diseases, encompassing a large panel of inflammator...
WP3

Impact Crohn

Impact of the Fecal Flora Transplantation on Crohn's DiseaseCrohn's disease is a chronic and relapsing inflammatory bowel disease. Many data show that the intestinal flora is involved in the disease and it has been show t...
WP3

MSIL2

Biological activity and safety of low dose IL2 in Relapsing Remitting Multiple Sclerosis​
Interleukin‐2 (IL‐2) was initially discovered and used as a stimulator of effector T lymphocytes (Teffs), but is now viewed as a very promising...